Kefiran Reduces Atherosclerosis in Rabbits Fed a High Cholesterol Diet
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چکیده
منابع مشابه
Spirulina prevents atherosclerosis by reducing hypercholesterolemia in rabbits fed a high-cholesterol diet.
The anti-atherogenic effects of spirulina (Spirulina platensis) were investigated in the New Zealand White (NZW) rabbit model. The animal had hypercholesterolemia induced by being fed a high cholesterol diet (HCD) containing 0.5% cholesterol for 4 wk, and then fed a HCD supplemented with 1 or 5% spirulina (SP1 or SP5) for an additional 8 wk. Spirulina supplementation lowered intimal surface of ...
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Previous studies have attempted to demonstrate the reversibility of rabbit atherosclerosis after discontinuance of cholesterol feeding or by other measures. These attempts have been largely unsuccessful. In all the studies, atherosclerosis was induced by cholesterol feeding for several months. At the end of these prolonged periods, the animals had advanced aortic lesions. The present study soug...
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Objectives: Lallemantia royleana (Benth. in Wall.) Benth. (Lamiaceae) is a medicinal plant used in Iranian traditional and folklore medicine in the treatment of various nervous, hepatic, and renal diseases. In the present study, whole seeds of the herb were prepared and evaluated for hypolipidemic activities using an animal model. Materials and Methods: Animals were fed normal diets or diets su...
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Oxidized lipoproteins may play a role in atherosclerosis. Recently, we have demonstrated that the levels of oxidized fatty acids in the circulation correlate directly with the quantity of oxidized fatty acids in the diet and that dietary oxidized fatty acids accelerate atherosclerosis in rabbits. The present study tests the hypothesis that oxidized cholesterol in the diet accelerates the develo...
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Rabbits were fed a low cholesterol atherogenic diet for up to 5 years. Arterial lesions during the first 12 months consisted of smooth muscle cell and lipid accumulation in the intima, with smaller amounts of elastin and collagen. By 24 months, considerable degeneration and necrosis of smooth muscle foam cells had occurred, lipid had decreased in relative proportion, and collagen was predominan...
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ژورنال
عنوان ژورنال: Journal of Atherosclerosis and Thrombosis
سال: 2010
ISSN: 1880-3873,1340-3478
DOI: 10.5551/jat.4812